Adaptive Optics
The goal of this project is to build an Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO) for imaging the human foveal cone mosaic. The completed system will be used to measure subjects' foveal cone density for studying the relationship between fixational eye movements and foveal characteristics. The system we're building is based on a similar system built and used by Austin Roorda's lab at UC Berkeley.
Presentations and Posters
Poster at CVS retreat, Feb 14, 2020. Gives a general overview of the motivation and goals for the project.
CVS retreat poster, 2/14/20
Presentation at lab meeting on March 31, 2020. Overview of system requirements and specifications, update on progress, and brief laser safety information.
Lab presentation, 3/31/20
Presentation with project team (Martina, Michele, Jannick, Ruei) on June 19, 2020 (updated July 13, 2020). Results of optical modeling and sensitivity analysis.
Sensitivity analysis report, 7/13/20
Presentation at lab meeting on August 4, 2020. Summary of sensitivity analysis results and overview of current progress on optical system alignment.
Lab presentation, 8/4/20
Presentation at project team meeting on August 18, 2020 to discuss remaining electronics components that we need to procure and how they interface.
AOSLO electronics overview, 8/18/20
Presentation at technical lab meeting on October 30, 2020. Summary of current progress and goals/timeline for the remainder of the project
Lab presentation, 10/30/20
Presentation at lab meeting on March 9, 2021. Progress update summarizing results from realignment with new galvo, pupil plane alignment, and electronics.
Lab presentation, 3/9/21
Presentation at technical lab meeting on July 9, 2021. Progress update on wavefront sensor calibration, AO in closed-loop mode, and pinhole alignment.
Lab presentation, 7/9/21
Presentation at technical lab meeting on September 8, 2021. Progress update on imaging a distortion grid and various imaging optimization steps.
Lab presentation, 9/8/21
Presentation at science lab meeting on March 22, 2022. Report of the first images from the system and the current video and image processing techniques.
Lab presentation, 3/22/22
Poster at the CVS retreat on March 25, 2022. Shows the system alignment and validation steps and some of the first images collected with the system.
CVS retreat poster, 3/25/22
Laser Safety Documentation
The laser used for this system is a Class 4 laser (the most dangerous class of lasers with the greatest potential for injury). As such, there are registration, inspection, other documentation requirements to ensure safe operation of the laser. Completed documents are displayed below. The laser inspection form must be updated and submitted to Environmental Health and Safety annually.
Laser Inspection Form
Laser Registration Form
Laser Standard Operating Procedures (SOP)
Laser Safety Training
All users of the Adaptive Optics system must be up to date with their laser training from Environmental Health and Safety. This training must be completed at least once every 3 years. It can be accessed via MyPath. After signing in to MyPath, search 'Laser Safety Training' and select the most up-to-date training module (listed as 'EHS Laser Safety Training 2022' at the time of writing this). Completed transcripts for the training should be saved in this folder on Box: '\APLab-Projects\AO\LaserSafety\LaserSafetyTrainingDocs'.